By David Y. Hwang
50 stories each Neurologist should still Know offers key stories that form the present medical perform of neurology. All neurologic subspecialties are lined, with a different emphasis on neurocritical care and vascular neurology. for every learn, a concise precis is gifted with an emphasis at the effects and barriers of the examine, and its implications for perform. An illustrative scientific case concludes each one evaluation, by means of short details on different correct stories. this is often the 1st publication of its style to offer a set of the main influential medical trials in neurology which are designated sufficient for use on rounds, yet nonetheless simply digestible. it's a must-read for health and wellbeing care pros and someone who desires to examine extra in regards to the information at the back of medical practice.
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Extra info for 50 studies every neurologist should know
Who Was Excluded: Patients were excluded if they (1) were aged <4 years, (2) had acute symptomatic seizures (such as febrile seizures), and (3) had a history of progressive neurologic disease. 1 for the study design. Study Design Drug Lamotrigine Topiramate Valproate Randomized Patients Allocated (N = 716) 239 239 238 Study Intervention: After the initial choice of drug was randomized, clinicians decided subsequent changes in dose or preparation, to most accurately mirror everyday practice. Online guidelines were available for clinicians as needed.
N Engl J Med. 2012;366(10):893–903. The MMSE scores for inclusion here were 5–13. Multiple types of cholinesterase inhibitors were included (donepezil, rivastigmine, galantamine) and, as noted, the MMSE range included both moderate and mild AD (memantine has not shown benefit for the mild group in multiple studies). See Porsteinsson AP, Grossberg GT, Mintzer J, Olin JT; Memantine MEM-MD-12 Study Group. Memantine treatment in patients with mild to moderate Alzheimer’s disease already receiving a cholinesterase inhibitor: a randomized, double-blind, placebo- controlled trial.
Emerg Med J. 2002;19:96–100. 3. Brophy G, Bell R, Claassen J, Alldredge B, et al. Guidelines for the evaluation and management of status epilepticus. Neurocritcal Care. 2012;17(1):3–23. 4. Shaner DM, McCurdy SA, Herring MO, Gabor AJ. Treatment of status epilepticus: a prospective comparison of diazepam and phenytoin versus phenobarbital and optional phenytoin. Neurology. 1988;38:202–207. 5. Alldredge BK, Gelb AM, Isaacs SM, et al. A comparison of lorazepam, diazepam, and placebo for the treatment of out-of-hospital status epilepticus.
50 studies every neurologist should know by David Y. Hwang